il 1

IL-1 α

E13-029-1 10μg
EUR 213

IL-1 beta, rat recombinant

P1019-1 1 mg
EUR 7288
Description: Interleukin 1 beta (IL-1?) is a proinflammatory cytokine and is produced by activated macrophages, monocytes, keratinocytes and other epithelial cells. Both IL-1? and IL-1? bind to the same receptor and have similar biological properties.

Anti-IL1R2/Il 1 Rii Antibody

A03106-1 1 ml
EUR 397
Description: Rabbit Polyclonal IL1R2/Il 1 Rii Antibody. Validated in IP, WB and tested in Human.

Recombinant Rat IL-1 Beta Protein

PROTQ63264-1 10ug
EUR 317
Description: IL-1β is a proinflammatory cytokine produced in a variety of cells including monocytes, tissue macrophages, keratinocytes and other epithelial cells. Both IL-1α and IL-1β binds to the same receptor and has similar if not identical biological properties. These cytokines have a broad range of activities including, stimulation of thymocyte proliferation, by inducing IL-2 release, B-cell maturation and proliferation, mitogenic FGF-like activity and the ability to stimulate the release of prostaglandin and collagenase from synovial cells. However, whereas IL-1β is a secreted cytokine, IL-1α is predominantly a cell-associated cytokine. Recombinant rat IL-1β is a 17.4 kDa protein containing 153 amino acid residues.

Canine IL-1 alpha Recombinant Protein

R01144-1 5ug/vial
EUR 259
Description: IL-1 alpha (IL-1α, IL-1F1) is a member of the interleukin 1 family of cytokines. IL-1 alpha is an inflammatory cytokine active in the initiation of the inflammatory reaction and in driving Th1 and Th17 inflammatory responses. Canine IL-1 alpha Recombinant Protein is purified interleukin-1 alpha cytokine produced in yeast.

Canine IL-1 beta Recombinant Protein

R00101-1 5ug/vial
EUR 259
Description: IL-1 beta (IL-1β) is a member of the interleukin 1 family of cytokines. The IL-1 beta cytokine is produced by activated macrophages as a proprotein, which is proteolytically processed to its active form by caspase 1 (CASP1/ICE). This cytokine is an important mediator of the inflammatory response, and is involved in a variety of cellular activities, including cell proliferation, differentiation, and apoptosis. Canine IL-1 beta Recombinant Protein is purified interleukin-1 beta cytokine produced in yeast.

IL-1-beta Interleukin-1 betaHuman Recombinant Protein

PROTP01584-1 Regular: 10ug
EUR 317
Description: Interleukin-1 beta Human Recombinant produced in E.Coli is a non-glycosylated, Polypeptide chain containing 153 amino acids and having a molecular mass of 17000 Dalton.;The IL-1b is purified by proprietary chromatographic techniques.

Recombinant Murine IL-17 (IL-17A) Protein

PROTQ62386-1 25ug
EUR 317
Description: The originally described IL-17 protein, now known as IL-17A, is a disulfide linked homodimer, secreted by activated T-cells that act on stromal cells to induce production of proinflammatory and hematopoietic bioactive molecules. Today, IL-17 represents a family of structurally-related cytokines that share a highly conserved C-terminal region but differ from one another in their N-terminal regions and in their distinct biological roles. The six known members of this family, IL-17A through IL-17F, are secreted as homodimers. IL-17A exhibits cross-species bioactivity between human and murine cells. Recombinant murine IL-17A is a 30.0 kDa disulfide-linked homodimer of two 133 amino acid polypeptide chains.

Human Interleukin-1 beta (IL-1 beta) AssayMax ELISA Kit

EI2200-1 96 Well Plate
EUR 477

Human Interleukin-1-alpha (IL-1-alpha) AssayMax ELISA Kit

EI2301-1 96 Well Plate
EUR 477

Mouse Interleukin-1 beta (IL-1 beta) AssayMax ELISA Kit

EMI2200-1 96 Well Plate
EUR 477

IL-2

E13-013-1 10μg
EUR 161

IL-4

E13-015-1 10μg
EUR 161

IL-6

E13-016-1 10μg
EUR 161

IL-1-alpha Interleukin-1 alpha Mouse Recombinant Protein, His Tag

PROTP01582-1 Regular: 20ug
EUR 317
Description: IL 1 alpha Mouse Recombinant produced in E.Coli is a single, non-glycosylated polypeptide chain containing 179 amino acids (115-270 a.a) and having a molecular mass of 20.4kDa.;IL 1 alpha is fused to a 23 amino acid His-tag at N-terminus & purified by proprietary chromatographic techniques.

IL-1-alpha Interleukin-1 alpha Human Recombinant Protein, His Tag

PROTP01583-1 Regular: 20ug
EUR 317
Description: IL-1A Human Recombinant produced in E.Coli is single, a non-glycosylated, Polypeptide chain containing 159 amino acids fragment (113-271) with an amino-terminal hexahistidine tag and having a total molecular mass of 22.5kDa. ;The Interleukin-1 alpha His-tag is purified by proprietary chromatographic techniques.

IL-1-beta Interleukin-1 beta Mouse Recombinant Protein, His Tag

PROTP10749-1 Regular: 25ug
EUR 317
Description: Interleukin-1 beta Mouse Recombinant produced in E.Coli is a non-glycosylated, Polypeptide chain containing 189 amino acids and having a molecular mass of 21 kDa. ;The IL-1b is fused to His-Tag and purified by proprietary chromatographic techniques.

IL-1-alpha Interleukin-1 alpha Rat Recombinant Protein, His Tag

PROTP16598-1 Regular: 20ug
EUR 317
Description: IL 1 alpha Rat Recombinant produced in E.Coli is a single, non-glycosylated polypeptide chain containing 179 amino acids (115-270 a.a) and having a molecular mass of 20.2kDa.

Anti-IL-31 Antibody

A08339-1 100ug/vial
EUR 334

Anti-IL-17B Antibody

A10846-1 100ul
EUR 397
Description: Rabbit Polyclonal Antibody for IL-17B Antibody (IL17B) detection.tested for IHC in Human, Rat.

Anti-IL-6 Antibody

A00102-1 100ug
EUR 432
Description: Rabbit Polyclonal IL-6 Antibody. Validated in Neu, IHC, WB and tested in Human.

IL-1beta, human recombinant

P1018-1 1 mg
EUR 5061
Description: Interleukin 1 beta (IL-1?) is a proinflammatory cytokine and is produced by activated macrophages, monocytes, keratinocytes and other epithelial cells

IL-2, human recombinant

P1020-1 1 mg
EUR 1156
Description: Interleukin 2 (IL2) is a secreted cytokine that is important for the proliferation of T and B lymphocytes and is produced by activated CD4+ and CD8+ T cells, gamma ? T cells, B cells, dendritic cells and eosinophils. IL-2 plays a critical role in immune responses against pathogenic infection

IL-3, human recombinant

P1021-1 1 mg
EUR 4017
Description: Interleukin 3 (IL-3) is a pleiotropic cytokine produced by activated T cells, mast cells and eosinophils, and stimulates the proliferation and differentiation of pluripotent hematopoietic stem cells, and committed progenitor cells of the megakaryocyte

IL-4, murine recombinant

P1022-1 1 mg
EUR 4504
Description: IL-4 is a pleiotropic cytokine produced by activated T lymphocytes, basophils, mast cells and bone marrow stromal cells. IL-4 plays an important role in the regulation of isotype switching, differentiation of precursor T helper cells and induction of IgE production in B lymphocytes.

IL-6, rat recombinant

P1023-1 1 mg
EUR 6940
Description: Interleukin-6 (IL-6) is a pleiotropic cytokine produced by activated T cells, monocytes, fibroblasts, endothelial cells, keratinocytes and macrophages, and plays an critical role in host defense by regulating immune and inflammatory responses.

IL-7, human recombinant

P1024-1 1 mg
EUR 6940
Description: Interleukin-7 (IL-7) is a potent lymphoid cell growth factor produced by bone marrow and thymic stromal cells, spleen cells and keratinocytes. IL7 stimulates the proliferation of Pre-B, Pro-B and early T cells.

IL-7, murine recombinant

P1025-1 1 mg
EUR 6940
Description: Interleukin-7 (IL-7) is a potent lymphoid cell growth factor produced by bone marrow and thymic stromal cells, spleen cells and keratinocytes. IL7 stimulates the proliferation of Pre-B, Pro-B and early T cells.

IL-1RA Interleukin-1 Receptor Antagonist Mouse Recombinant Protein

PROTP25085-1 Regular: 20ug
EUR 317
Description: IL1 ra Mouse Recombinant produced in E.Coli is a single, non-glycosylated polypeptide chain containing 153 amino acids and having a molecular mass of 17.4kDa. ;The IL1ra is purified by proprietary chromatographic techniques.

His-IL-3

E13-014-1 10μg
EUR 161

His-IL-10

E13-019-1 10μg
EUR 161

His-IL-22

E13-028-1 10μg
EUR 213

IL-2-Fc

E13-m007-1 10μg
EUR 310

Anti-IL-22/IL22 Antibody

A00963-1 100ug/vial
EUR 294

Anti-IL-3R beta Antibody

A02219-1 100ul
EUR 397
Description: Rabbit Polyclonal Antibody for IL-3R beta Antibody (CSF2RB) detection.tested for WB in Human, Mouse, Rat.

Anti-IL-2/IL2 Antibody

A00387-1 100ug/vial
EUR 294

Anti-IL-8 Monoclonal Antibody

A00423-1 100ul
EUR 397
Description: Mouse Monoclonal Antibody for IL-8 Antibody (CXCL8) detection. Tested with IHC in Human, Mouse, Rat.

Anti-IL-6 Monoclonal Antibody

M00102-1 100ug
EUR 455
Description: Mouse Monoclonal IL-6 Antibody. Validated in Flow Cytometry, WB and tested in Human.

Anti-IL-17A Monoclonal Antibody

M00421-1 100ug
EUR 455
Description: Mouse Monoclonal IL-17A Antibody. Validated in WB and tested in Human.

IL-10, human recombinant protein

P1028-1 1 mg
EUR 6731
Description: Interleukin-10 (IL-10) is an immunosuppressive cytokine produced by macrophages, monocytes, T cells, B cells and keratinocytes. IL-10 inhibits the synthesis of proinflammatory cytokines such as IL-1 and TNF-? and proliferation of T cells

IL-15, human recombinant protein

P1029-1 1 mg
EUR 5339
Description: Interleukin 15 (IL-15) is an immunomodulating cytokine mainly produced by adherent peripheral blood mononuclear cells, fibroblasts and epithelial cells and stimulates the proliferation of T lymphocytes.

IL-17A, human recombinant protein

P1030-1 1 mg
EUR 4156
Description: Interleukin-17A (IL-17A) is a proinflammatory cytokine produced by Th17 cells. IL-17 regulates the activities of NF-kappaB and mitogen-activated protein kinases and stimulates the expression of IL6 and cyclooxygenase-2 (PTGS2/COX-2), as well as the production of nitric oxide (NO).

IL-17A, rat recombinant protein

P1031-1 1 mg
EUR 4156
Description: Interleukin-17A (IL-17A) is a proinflammatory cytokine produced by Th17 cells. IL-17 regulates the activities of NF-kappaB and mitogen-activated protein kinases and stimulates the expression of IL6 and cyclooxygenase-2 (PTGS2/COX-2), as well as the production of nitric oxide (NO)

IL-18, human recombinant protein

P1032-.1 100 µg
EUR 780
Description: Interleukin-18 (IL-18) is a proinflammatory cytokine produced by monocyte/macrophages, osteoblasts and keratinocytes, as a proprotein which is proteolytically processed to its active form by caspase-1. Human IL-18 can enhance NK cell activity in PBMC cultures.

IL-18, human recombinant protein

P1032-1 1 mg
EUR 5061
Description: Interleukin-18 (IL-18) is a proinflammatory cytokine produced by monocyte/macrophages, osteoblasts and keratinocytes, as a proprotein which is proteolytically processed to its active form by caspase-1. Human IL-18 can enhance NK cell activity in PBMC cultures.

IL-21, human recombinant protein

P1033-1 1 mg
EUR 6522
Description: Interleukin-21 (IL-21) is a pleiotropic cytokine produced by CD4+ T cells in response to antigenic stimulation. IL-21 induces the differentiation of T-cell-stimulated B-cells into plasma cells and memory B-cells, apoptotic effects in naïve B-cells.

Recombinant Murine IL-11 Protein

PROTP47873-1 10ug
EUR 317
Description: IL-11 is a multifunctional cytokine produced by stromal cells such as fibroblasts, epithelial cells and osteoclasts. It is expressed in a wide variety of tissues including thymus, lung, bone, connective tissue and central nervous system. IL-11 plays an important regulatory role in hematopoiesis by stimulating growth of myeloid, erythroid and megakaryocyte progenitor cells. It also regulates bone metabolism, inhibits production of proinflammatory cytokines and protects against gastromucosal injury. Recombinant Murine IL-11 is a 19.1 kDa protein consisting of 179 amino acid residues.

Recombinant Rat IL-7 Protein

PROTP56478-1 10ug
EUR 317
Description: IL-7 is a hematopoietic growth factor which affects primarily early B and T cells. Produced by thymic stromal cells, spleen cells and keratinocytes, IL-7 can also co-stimulate the proliferation of mature T cells in combination with other factors such as ConA and IL-2. Human and murine IL-7 is cross-species reactive. Recombinant rat IL-7 is a 15.0 kDa protein containing 130 amino acid residues.

Recombinant Rat IL-15 Protein

PROTP97604-1 10ug
EUR 317
Description: IL-15 is an immunomodulating cytokine that stimulates the proliferation of T lymphocytes and shares many biological properties with IL-2. IL-15 exerts its biological activites primarily on T cells. It is also essential in the development, survival and activation of NK cells. Increased expression of IL-15 has been implicated with rheumatoid arthritis, inflammatory bowl disease and diseases affiliated with retroviruses HIV and HTLV-I. Human IL-15 is biologically active on mouse cells as measured by the dose-dependent stimulation of the proliferation of mouse CTLL cells. Recombinant rat IL-15 is a 13.5 kDa protein consisting of 115 amino acid residues.

Recombinant Rat IL-5 Protein

PROTQ08125-1 10ug
EUR 317
Description: IL-5 is a hematopoietic growth factor that stimulates the proliferation and activation of eosinophils. Produced by mast cells, T cells, and eosinophils, IL-5 plays an important role in inducing cell-mediated immunity against parasitic infections and certain tumors. Elevated levels of IL-5 lead to Eosinophilia, which may result in the induction of asthma and other allergic diseases. Recombinant rat IL-5 is a 26.0 kDa disulfide-linked homodimeric protein containing two 113 amino acid chains.

Recombinant Human IL-24 Protein

PROTQ13007-1 20ug
EUR 317
Description: IL-24 is a secreted glycoprotein belonging to the IL-10 structural family of cytokines. It is produced by a variety of cell types, including B cells, CD4+ cells, NK cells, lymph node DCs, monocytes, and melanoma cells. IL-24 can signal through the IL20R1/IL20R2 and IL22R1/IL20R2 receptors to initiate a signaling cascade which includes the induction of JAK1/STAT3 phosphorylation. IL-24 is, functionally, a pleiotropic protein but is generally characterized as an anti-cancer cytokine that can selectively inhibit growth of a wide variety of human cancer cells through activities that include the induction of differentiation and apoptosis, and the suppression of angiogenesis and cell proliferation. Recombinant human IL-24 is an 18.9 kDa glycoprotein, containing 161 amino acid residues, including a C-terminal His-tag.

Recombinant Murine IL-31 Protein

PROTQ6EAL8-1 10ug
EUR 317
Description: IL-31 is a T-cell derived cytokine that shares several structural and functional characteristics with IL-6, Oncostatin M, LIF, and Cardiotrophin-1. It signals through a receptor complex comprised of GPL (GP130-like, IL-31RA) and OSMR (Oncostatin M receptor). GPL/OSMR signaling is a strong activator of STAT3 and STAT5, and can also activate STAT1, Jak1, and Jak2 signaling pathways. IL-31 regulated immune responses have been implicated in skin physiology and inflammatory skin diseases. Recombinant murine IL-31 is a 15.8 kDa protein containing 140 amino acid residues.

Recombinant Human IL-31 Protein

PROTQ6EBC2-1 10ug
EUR 317
Description: Human IL-31 is a T-cell derived cytokine that shares several structural and functional characteristics with IL-6, Oncostatin M, LIF, and Cardiotrophin-1. It signals through a receptor complex comprised of GPL (GP130-like, IL-31RA) and OSMR (Oncostatin M receptor). GPL/OSMR signaling is a strong activator of STAT3 and STAT5, and can also activate STAT1, Jak1, and Jak2 signaling pathways. IL-31 regulated immune responses have been implicated in skin physiology and inflammatory skin diseases. Recombinant IL-31 is a 15.8 kDa protein containing 141 amino acid residues.

Recombinant Murine IL-17F Protein

PROTQ7TNI7-1 25ug
EUR 317
Description: IL-17F, a member of the IL-17 family of structurally related cytokines, has been shown to stimulate proliferation and activation of T-cells and PBMCs. IL-17F also regulates cartilage matrix turnover and inhibits angiogenesis. Recombinant murine IL-17F is a disulfide-linked homodimer of 30 kDa, consisting of two 134 amino acid residue chains.

Recombinant Human IL-17D Protein

PROTQ8TAD2-1 25ug
EUR 317
Description: IL-17D is a disulfide-linked homodimer of two 185 amino acid polypeptide chains. It belongs to the IL-17 family of structurally-related cytokines that share a highly conserved C-terminal region but differ from one another in their N-terminal regions and in their distinct biological roles. The six known members of this family, IL-17A through IL-17F, are secreted as homodimers. IL-17D has the ability to stimulate the production of IL-6, IL-8, and GM-CSF and inhibits hemopoiesis of myeloid progenitor cells in colony forming assays. Recombinant human IL-17D is a 40.5 kDa disulfide-linked homodimer of two 185 amino acid polypeptide chains.

Recombinant Murine IL-21 Protein

PROTQ9ES17-1 10ug
EUR 317
Description: IL-21 is a pleiotropic cytokine produced by CD4+ T cells in response to antigenic stimulation. Its action generally enhances antigen-specific responses of immune cells. The biological effects of IL-21 include induction of differentiation of T-cells-stimulated-B-cells into plasma cells and memory B-cells, stimulation (in conjunction) with IL-4 of IgG production, and induction of apoptotic effects in naïve B-cells and stimulated B-cells in the absence of T-cell signaling. Additionally, IL-21 promotes the anti-tumor activity of CD8+ T-cells and NK cells. IL-21 exerts its effect through binding to a specific type I cytokine receptor, IL-21R, which also contains the γ chain (γc) found in other cytokine receptors including IL-2, IL-4, IL-7, IL-9 and IL-15. The IL-21/IL-21R interaction triggers a cascade of events which includes activation of the tyrosine kinases JAK1 and JAK3, followed by activation of the transcription factors STAT1 and STAT3. Recombinant murine IL-21 is a 15.0 kDa protein consisting of 130 amino acid residues.

Recombinant Human IL-22 Protein

PROTQ9GZX6-1 10ug
EUR 317
Description: IL-22 is a member of the IL-10 family of regulatory cytokines which includes IL-10, IL-19, IL-20, IL-22, IL-24 and IL-26. Members of this family share partial homology in their amino acid sequences, but they are dissimilar in their biological functions. Produced by T lymphocytes, IL-22 inhibits IL-4 production by Th2 cells, and induces acute phase reactants in the liver and pancreas. IL-22 signals through a receptor system consisting of IL-10R-β/CRF2-4 and IL-22R, both of which are members of the class II cytokine-receptor family. Recombinant human IL-22 is a 33.6 kDa non-disulfide-linked homodimeric protein containing of two 146 amino acid polypeptide chains.

Recombinant Human IL-17E Protein

PROTQ9H293-1 25ug
EUR 317
Description: IL-17E is a disulfide-linked homodimer of two 145 amino acid polypeptide chains. It belongs to the IL-17 family of structurally-related cytokines that share a highly conserved C-terminal region, but differ from one another in their N-terminal regions and in their distinct biological roles. The six known members of this family, IL-17A through IL-17F, are secreted as homodimers. IL-17E stimulated secretion of IL-8, and induces activation of the transcription factor NF-κB in cells that express the IL-17BR receptor. Recombinant human IL-17E is a 33.8 kDa disulfide-linked homodimer of two 145 amino acid polypeptide chains.

Recombinant Human IL-20 Protein

PROTQ9NYY1-1 10ug
EUR 317
Description: IL-20 is a member of the IL-10 family of regulatory cytokines which includes IL-10, IL-19, IL-20, IL-22, IL-24 and IL-26. Members of this family share partial homology in their amino acid sequences but they are dissimilar in their biological functions. IL-20 is a hematopoietic growth factor capable of stimulating colony formation by CD34+ multipotential progenitors, but not by other progenitor cells. IL-20 signals through a receptor system composed of type I IL-20R-α and type II IL-20R-β. Over-expression of IL-20 in keratinocytes expressing both receptor subunits has been implicated in the induction of inflammatory skin disease. Recombinant human IL-20 is a 35.2 kDa homodimeric protein consisting of two 153 amino acid polypeptide chains.

Recombinant Human IL-19 Protein

PROTQ9UHD0-1 10ug
EUR 317
Description: IL-19 belongs to the IL-10 family of regulatory cytokines which includes IL-10, IL-19, IL-20, IL-22, IL-24 and IL-26. Members of this family share partial homology in their amino acid sequences but they are dissimilar in their biological functions. Preliminary data suggests that IL-19 is a proinflammatory cytokine because it up-regulates IL-6 and TNF-α and induces apoptosis through TNF-α. IL-19 signals through the type I IL-20R. Human and murine IL-19 share 71% amino acid sequence identity. Recombinant human IL-19 is a 17.9 kDa protein containing 153 amino acid residues. In solution IL-19 exists predominantly as a non-disulfide-linked dimer.