Technology
Orla technology overcomes existing limitations to the manufacture of biological surfaces. Orla has patented, developed and commercialised a biosurface engineering technology which radically simplifies the way in which proteins are immobilised on surfaces. This leads to dramatic improvements in functionality, utility and manufacture.
The technology is simple and elegant as can be seen in the schematic below;
Existing Surfaces |
Orla Surfaces |
| Poor Orientation High Background Low Signal to Noise Poor reproducibility Physical adsorption or complex chemistry Surface density low Scale up problematic Limited Control Reduced Functionality Lacking Quality Assurance methods |
Protein orientation is controllable Non specific interactions are minimal High signal to noise Self assembly is highly reproducible Simple assembly from aqueous solution High density/controllable Easily scaled, manufacturable and cost effective Exquisite control of surface assembly Proteins retain functionality All surfaces and proteins fully characterised and quality controlled |
By comparison, existing surface chemistries cannot match the performance of Orla surfaces – and the company’s biosurface engineering technology provides a core platform for further product development opportunities.
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