The Orla Solution
Orla technology overcomes existing limitations to the manufacture of biological surfaces. Orla has patented, developed and commercialised a technology which radically simplifies the way in which proteins are immobilised on surfaces. This leads to dramatic improvements in functionality, utility and manufacture.
The technology is simple and elegant as can be seen in the schematic below;
Existing Surface Chemistries |
Orla Products |
Poor Orientation |
Protein orientation is controllable |
High Background |
Non specific interactions are minimal |
Low Signal to Noise |
High signal to noise |
Poor reproducibility |
Self assembly is highly reproducible |
Physical adsorption or complex chemistry |
Simple assembly from aqueous solution |
Surface density low |
High density/controllable |
Scale up problematic |
Easily scaled, manufacturable and cost effective |
Limited Control |
Exquisite control of surface assembly |
Reduced Functionality |
Proteins retain functionality |
Lacking Quality Assurance methods |
All surfaces and proteins fully characterised and quality controlled |
In direct comparison existing surface chemistries cannot match the performance of the Orla surfaces. The technology provides a core platform for further product development opportunities in the future. Orla technology not only improves upon current methods, it also opens the door to novel and innovative surface applications that would not be possible without the unique Orla technology.
For more information about the Orla solution contact us or visit the frequently asked questions section.
11/01/2010. There is an increasing demand from the pharmaceutical and biotechnology industries for methods to replace the use of animals in drug testing. ...more
4th March 2010 - Orla's founder and Scientific director, Professor Jeremy Lakey, will be presenting at the sensors and instrumentation knowledge transfer network ...more